Un Docente Universitario italiano affermò in una mail, a me indirizzata, che hanno valore scientifico i “lunghi” articoli, pubblicati su peerr-reviews! Di seguito, una ennesima smentita alla sua storia metropolitana.
To JAMA, NEJM, Lancet, Ann.Int. Med. Editors,
to Prof. Jeff D. Williamson,
Jeff D. Williamson, MD, MHS, et al. (Exactly 24 Authors), Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years. A Randomized Clinical Trial. JAMA. 2016;315(24):2673-2682. doi:10.1001/jama.2016.7050. http://jama.jamanetwork.com/article.aspx?articleid=2524266 conclude:
"Among ambulatory adults aged 75 years or older, treating to an SBP target of less than 120 mm Hg compared with an SBP target of less than 140 mm Hg resulted in significantly lower rates of fatal and nonfatal major cardiovascular events and death from any cause".
According to Quantum Biophysical Semeiotic, such a conclusion is fundamentally biased, because the 25 Authors, who signed the article, as well as JAMA Editors ans Reviewers, ignore what does it mean ATS-Dependent, CAD Inherited Real Risk , so that the subjects enrolled in the research aren’t all involved by it:
REFERENCES
1) Sergio Stagnaro (29 May 2008) Bedside Recognizing CAD Inherited Real Risk and silent CAD with Biophysical Semeiotics. http://www.lipidworld.com/content/7/1/19/comments
2) Sergio Stagnaro and Simone Caramel (2012) Quantum Biophysical Semeiotics Microcirculatory Theory of Arteriosclerosis – www.sisbq.org, Journal of Quantum Biophysical Semeiotics, first version, http://www.sisbq.org/uploads/5/6/8/7/5687930/ats_qbs__mctheory.pdf
3) Sergio Stagnaro, Use of multiple markers and improvement of the prediction model for cardiovascular mortality, www.nature.com, 21 May, 2008 http://network.nature.com/forums/pmgs/1587?page=1
4) Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial Oxygenation and Biophysical-Semeiotic Preconditioning. International Atherosclerosis Society. www.athero.org, 29 April, 2009 http://www.athero.org/commentaries/comm907.asp
5) Sergio Stagnaro Bed-side biophysical semeiotic recognizing CAD “inherited real risk” and overt CAD, event silent. l: (18 October 2003). www.bmj.com, http://www.bmj.com/cgi/eletters/327/7420/895
6) Sergio Stagnaro Assessing NK cell compartment in individuals with CAD Inherited Real Risk. Immunity & Aging, (14 May 2007), http://www.immunityageing.com/content/4/1/3/comments
7) Sergio Stagnaro. Bedside Biophysical-Semeiotic Recognizing CAD Real Risk and silent CAD. Journal Review, http://journalreview.org/v2/articles/view/16449729.html
8) Sergio Stagnaro. A Clinical Biophysical-Semeiotic Contribution reliable in prompt recognizing CAD, even silent. BMC.Cardiovascular Disorders, 2005, http://www.biomedcentral.com/1471-2261/5/5/comments
9) Sergio Stagnaro. Without CAD Inherited Real Risk,
All Environmental Risk Factors of CAD are innocent
Bystanders. Canadian Medical Association Journal.
CMAJ, 14 Dec 2009,
http://www.cmaj.ca/content/181/12/E267/reply
10) Stagnaro Sergio. Role of Coronary Endoarterial Blocking Devices in Myocardial Preconditioning – c007i. Lecture, V Virtual International Congress of Cardiology, 2007. http://www.fac.org.ar/qcvc/llave/c007i/stagnaros.php
11) Sergio Stagnaro. A Clinical Method far better than Blood Cell Count in CAD Primary Prevention. www.bmj.com, 2005, http://www.bmj.com/cgi/eletters/330/7493/690
12) New bedside way in Reducing mortality in diabetic men and women.
Ann Int Med.2007. http://www.annals.org/cgi/eletters/147/3/149
12) Sergio Stagnaro. Biophysical Semeiotics is really useful in order to bed-side recognizing heart ischaemic disease, even before its onset, i.e., real risk of coronary artery disease. BMC. Cardiovascular Diseases, 2004, http://www.biomedcentral.com/1471-2261/3/12/comments
13) Stagnaro Sergio. Bedside Evaluation of CAD biophysical-semeiotic inherited real risk under NIR-LED treatment. EMLA Congress, Laser Helsinki August 23-24, 2008. “Photodiagnosis and photodynamic therapy”, Elsevier, Vol. 5 suppl 1 august 2008 issn 1572-1000.
14) Sergio Stagnaro Biophysical-Semeiotic Diagnosing Cad “real” risk, as well as pre-clinical and clinical CAD. www.bmj.com, (12 September 2003) http://bmj.bmjjournals.com/cgi/eletters/327/7415/591
15) Sergio Stagnaro Bedside Biophysical Semeiotic Evaluation of Acute Phase Proteins. Ann Family Med. 2008, http://www.annfammed.org/cgi/eletters/6/2/100
16) Sergio Stagnaro. EBM “and” Single Patient Based Medicine, Medical News today, 2007, http://www.medicalnewstoday.com/youropinions.php?opinionid=23466
17) Sergio Stagnaro. Inherited Real Risk of CAD and Cancer, www.nature.com, 2008, http://blogs.nature.com/news/thegreatbeyond/2008/01/can_shining_lights_on_your_hea_1.html
18) Sergio Stagnaro (2012). I Segni di Caotino* e di Gentile** nella Diagnosi di Reale Rischio Congenito di CAD e di Infarto Miocardico, ancorché iniziale o silente. Fisiopatologia e Terapia. Lectio Magistralis. III Convegno della SISBQ, 9-10 Giugno 2012, Porretta Terme (Bologna). http://www.sisbq.org. http://www.sisbq.org/uploads/5/6/8/7/5687930/presentazione_stagnaro_it.pdf ; English version: http://www.sisbq.org/uploads/5/6/8/7/5687930/presentazione_stagnaro_eng.pdf
19) Stagnaro Sergio. Reale Rischio Semeiotico Biofisico. I Dispositivi Endoarteriolari di Blocco neoformati, patologici, tipo I, sottotipo a) oncologico, e b) aspecifico. Ediz. Travel Factory, www.travelfactory.it, Roma, 2009.
20) Simone Caramel and Sergio Stagnaro (2012). Vascular calcification and Inherited Real Risk of lithiasis. Front. In Endocrin. 3:119. doi: 10.3389/fendo.2012.00119
http://www.frontiersin.org/Bone_Research/10.3389/fendo.2012.00119/full [MEDLINE].
21) Sergio Stagnaro and Simone Caramel (2013). The Inherited Real Risk of Coronary Artery Disease, Nature PG., EJCN, European Journal Clinical Nutrition, Nature PG., 67, 683 (June 2013) | doi:10.1038/ejcn.2013.37, http://www.nature.com/ejcn/journal/v67/n6/full/ejcn201337a.html. [MEDLINE].
22) Sergio Stagnaro (2013). Two Clinical Evidences Corroborating Microcirculatory Quantum-Biophysical-Semeiotic Theory of Atherosclerosis. Lectio Magistralis, IV Congress of SISBQ, Porretta Terme (Bologna), 4-5 May, 2013 www.sisbq.org, http://www.sisbq.org/uploads/5/6/8/7/5687930/atherotheory_evidences.pdf
23) Sergio Stagnaro and Simone Caramel. The Key Role of Vasa Vasorum Inherited Remodeling in QBS Microcirculatory Theory of Atherosclerosis. Frontiers in Epigenomics and Epigenetics. http://www.frontiersin.org/Epigenomics_and_Epigenetics/10.3389/fgene.2013.00055/full [MEDLINE]
24) Sergio Stagnaro (2013). Two Clinical Evidences corroborating Microcirculatory QBS Theory of Atherosclerosis. Lectio Magistralis, IV Meeting of Quantum Biophysical Semeiotics International Society, May 4-5, 2013, Porretta Terme, Bologna, Auditorium, Hotel Santoli. Journal of QBS, http://www.sisbq.org/uploads/5/6/8/7/5687930/atherotheory_evidences.pdf
25) Sergio Stagnaro (2013). Abdominal Aortic Aneurism Inherited Real Risk: Patho-Physiology, Quantum-Biophysical-Semeiotic Symptomatology, Diagnosis and Therapy. www.sisbq.org. Journal of Quantum Biophysical Semeiotics. http://www.sisbq.org/uploads/5/6/8/7/5687930/aaa_irr_lectio_magistralis_2013.pdf
26) Sergio Stagnaro, Simone Caramel. Inherited Real Risk of Coronary Artery Disease: pathophysiology, diagnosis and primary prevention. Epidemiology and Cardiovascular Prevention. Brief Communication. 8th International Congress of Cardiology in the internet. Published: 28 October 2013. FAC Federaciòn Argentina de Cardiologia http://fac.org.ar/8cvc/llave/tl054_stagnaro/tl054_stagnaro.php – PDF
27) Sergio Stagnaro. CAD Inherited Real Risk In Preventing Myocardial Infarct. http://www.sci-vox.com, 13 September, 2010. http://www.sci-vox.com/stories/story/2010-09-13cad+inherited+real+risk+in+preventing++myocardial+infarct..html
28) Sergio Stagnaro. Reale Rischio Congenito di Infarto miocardio. Fondamentali Aspetti Teorici, 2014. www.sisbq.org, http://www.sisbq.org/uploads/5/6/8/7/5687930/rrcima2014_sstagnaro.pdf
29) Sergio Stagnaro. Reale Rischio Congenito di Infarto Miocardio, 20014. Diagnosi e Terapia. http://www.sisbq.org/uploads/5/6/8/7/5687930/rrcima2014_sstagnaro.pdf
30) Pyatakovich F.A., Stagnaro S., Caramel S., Yakunchenko T.I., Makkonen K.F., Moryleva O.N. Background Millimeter Radiation Influence in Cardiology on patients with metabolic and pre-metabolic syndrome. Journal of Infrared and Millimeter Waves, , Shanghai, China http://journal.sitp.ac.cn/hwyhmb/hwyhmben/ch/reader/view_abstract.aspx?file_no=120750&flag=131) Simone Caramel (2010). Coronary Artery Disease and Inherited Real Risk of CAD. Journal of Quantum Biophysical Semeiotics. http://www.sisbq.org/uploads/5/6/8/7/5687930/cad_caramel.pdf
32) Sergio Stagnaro, Simone Caramel. Inherited Real Risk of Coronary Artery Disease: pathophysiology, diagnosis and primary prevention. Epidemiology and Cardiovascular Prevention. Brief Communication. 8th International Congress of Cardiology in the internet. Published: 28 October 2013. FAC Federaciòn Argentina de Cardiologia http://fac.org.ar/8cvc/llave/tl054_stagnaro/tl054_stagnaro.php – PDF
33) Sergio Stagnaro and Simone Caramel. The Inherited Real Risk of Coronary Artery Disease, Nature PG., EJCN, European Journal Clinical Nutrition, Nature PG., http://www.nature.com/ejcn/journal/v67/n6/full/ejcn201337a.html [Medline]
34) Simone Caramel, Marco Marchionni and Sergio Stagnaro (2014). The Glycocalyx Bedside Evaluation Plays A Central Role in Diagnosing Type 2 Diabetes Mellitus and in its Primary Prevention. Treatment Strategies – Diagnosing Diabetes, Cambridge Research Centre, Volume 6 Issue 1, Pg 41-43. http://viewer.zmags.com/publication/0aafcae9#/0aafcae9/1
35) Mario Siniscalchi, Simone Caramel, Sergio Stagnaro (2016). Quando il fonendoscopio aiuta il cardiologo. Cuore e Vasi. Anno XXXVII • N. 3-4/2015, dicembre. Pg.15.
I am awaiting your critical comment.
Sincerely
Dr Sergio Stagnaro
Sergio Stagnaro MD
Via Erasmo Piaggio 23/8,
16039 Riva Trigoso (Genoa) Italy
Phone 0390-0185-42315
Founder of Quantum Biophysical Semeiotics,
Honorary President of International Society of
Quantum Biophysical Semeiotics (SISBQ)
www.semeioticabiofisica.it
www.sisbq.org
www.sergiostagnaro.wordpress.com
PS:
I will published this mail on La Voce di SS, because the diffusion of knowledge is the duty of every scientist
https://sergiostagnaro.wordpress.com