Moscatelli’s Sign: bedside recognizing in one second genital tract disorders, with a stehoscope.

Notoriously ovary cancer diagnosis is mainly late, so that its prognosis is really severe (1-5). In addition, it’s difficult bedside diagnosing an ovary cyst showing a diameter less than 3 cm. Interestingly, neither Laboratory nor Image Department can allow physician to diagnose ovary-, uterus- and cervical- cancer Inherited Real Risk (4).

From the clinical view-point, by means of Quantum Biophysical Semeiotics I observed well-defined microvascular modification of the local microcirculatory bed, both structural and functional in nature, in subjects involved by abnormalities of pschyco-neuro-endocrinological-immune system, i.e., in malignancy biological control system, I have termed Oncological Terrain (1-5).

Really, both genetically heritable and environmental risk factors induce contemporaneously parenchymal and microvascular cells alterations, according to Tiscendorf’s Angiobiotopie, I have completed with the Angiobiopathy Theory (1, 5). In a few words, all oncological cell-dependent events (control, regulation, duplication, a.s.o.), may happen only by means of singular changes in local structural and functional microcirculation, which notoriously supplies information-material-energy to related parenchymal cells(1-6).

Now-a-days, thanks to Quantum Biophysical Semeiotics, physicians can evaluate clinically microcirculatory bed structure and function in a precise manner, e.g., of cervical cancer inherited real risk, and overt cancer, of course, as well as of any biological systems, including lymphnodes and bone-marrow, assessing clinically local vasomotility and vasomotion (1, 5).

Evaluating properly the type of microcirculatory activation of cancer as well as of local lymphnodes and bone-marrow (type I, associated, physiological; type II, intermediate, partially dissociated, characteristic of real oncological risk, and finally type III, dissociated, indicating cancer onset) (1) we can assess in a quantitative way the alterations of physiological relation between vasomotility (= chaotic deterministic oscillations of small arterioles and arterioles, according to Hammersen, on the one hand, and vasomotion (= chaotic deterministic oscillations of related capillary and post-capillary primary venules), since the intensity of such as dissociation is correlated with the seriousness of underlying oncological disorders. As follows, a really easy way, to detect cervical cancer inherited real risk, and overt cancer is briefly described: in healthy woman, intense pinching XI dermatomere (the skin at groin level) does simultaneously bring about aspecific gastric reflex, immediately followed by tonic Gastric Contraction, typical of malignancy, even initial, due to the no-local realm in biological system. On the contrary, under above-illustrated, in women involved by cervical Cancer inherited real risk or suffering from cervical cancer, starting from the initial stage simultaneously appear such a reflex, followed by tonic Gastric Contraction, whose parameter values parallel the seriousness of underlying disorder.

First of all, doctor has to apply Moscatelli’s* Sign, that allows physician to bedside recognize in one second the presence of any genital tract disorder, both oncological and no oncological in nature.

In health, the intense compression between two digital pulps of the anterior-lower part of the helix does not simultaneously bring about gastric aspecific reflex: Moscatelli’s Sign negative.

On the contrary, in case of any disorder of genital tract, under above illustrated experimental condition, helix-gastric aspecific reflex appears simultaneously: Moscatelli’s Sign positive. Typically in presence of a cancer, even in its initial stage of Inherited Real Risk, a characteristic intense Gastric Tonic Contraction follows the aspecific gastric reflex.

As in all other cases the intensity in cm. of the reflex parallels the seriousnes of the underlying disorder. To recognize the False-Negative cases (10% about) very useful and reliable proved to be the numerous stress tests (7)

Soon there after, if Moscatelli’s Sign is positive, the physician performs the differential diagnosis with the aid of a flurry of Quantum Biophysical Semeiotic specific signs (1-7).

References

1) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno oncologic. Travel Factory SRL., Roma, 2004. http://www.travelfactory.it/semeiotica_biofisica.htm

2) Stagnaro Sergio. Fundamental Bias About Relation HPV and Cervical Cancer. BMJ, J Epidemiol Community Health, (3 March 2009). http://jech.bmj.com/cgi/eletters/62/7/570

3) Stagnaro Sergio. On preventing cervical cancer in Africa. 30 March 2009, by BMJ Group. http://blogs.bmj.com/bmj/2009/03/30/david-kerr-on- preventing-cervical-cancer-in-africa/

4) Sergio Stagnaro and Simone Caramel. Oncological Terrain-Dependent, Inherited Real Risk of Cervical Cancer: patophysiology, diagnosis and primary prevention – 2013. http://www.sisbq.org/uploads/5/6/8/7/5687930/cervicalcancerirr_2013.pdf

5) Sergio Stagnaro and Simone Caramel (2013). The Role of Modified Mediterranean Diet and Quantum Therapy in Oncological Primary Prevention. Current Nutrition & Food Science, Bentham PG., February, 2013, Upcoming Articles http://benthamscience.com/UpcomingArticles.php?JCode=CNF

6) Sergio Stagnaro and Simone Caramel. BRCA-1 and BRCA-2 mutation bedside detection and breast cancer clinical primary prevention. Front. Genet. | doi: 10.3389/fgene.2013.00039. http://www.frontiersin.org/Cancer_Genetics/10.3389/fgene.2013.00039/full [MEDLINE]

7) Sergio Stagnaro (2014). Ordine Implicato e Ordine Esplicato nel Segno di Rinaldi, simultaneo ed istantaneo: dal Terreno Oncologico all’Oncogenesi – http://www.sisbq.org, http://www.sisbq.org/uploads/5/6/8/7/5687930/rinaldi_simultaneo_2014.pdf

* Gilberto Moscatelly, my dearest Friend  and  beloved physician in Sestri Levante – Genoa –  In Memoriam

Pubblicità

Breast Cancer Defeated by Quantum Biophysical Semeiotics, the “Professors” not yet!

In following, I  illustrate  Bedside Detecting  Oncological Terrain-Dependent, Inherited Real Risk of Breast Cancer, which  plays a central Role in its Primary Prevention by means of no expensive therapy,  and thus we are able to defeat breast cancer, if we wont it, of course.

In spite of thousand peer reviews and million of paramount articles and Editorials,  Cancer, including Breast Cancer,  is today’s growing EPIDEMIC all around the world.

As a consequence, there is somethink wrong regarding the so-called epochal advances of international Oncology.

Aiming to lower the number of negative biopsies, and especially  aiming to avoid  useles breast biopsy, causing Psychological Jatrogenetic Terrorism (1), physicians have to familiarise with the concept of Oncological Terrain, as well as OT-Dependent, Inherited Real Risk (1-12), obtaining  the best   results in the war against breast cancer (2-7).

There is a general agreement that Primary, and especially Pre-Pimary Prevention http://www.sisbq.org/qbs-magazine.html, ignored unfortunately by “Professors”, is far better than every therapy

At this point, I emphasise that, even the surgical operation, the only efficacious tool in removing an “initial” small cancer,  cannot eliminate Oncological Terrain and possible OT-dependent, Inherited Real Risk!

Based on 55 year-long, well-established clinical experience, for all women (and men, too!), an original clinical assessment, unavoidable also to breast biopsy,  proved to be useful and reliable, applied easily, and quickly, allowing to bedside recognize the presence of maternally-inherited, functional mitochondrial cytopathy, termed Congenital Acidosic-Enzyme Metabolic Histangiopathy, Oncological Terrain, conditio sine qua non of cancer, is based on (1-10).

In fact, it is sufficient ascertaining breast cancer Oncological Terrain-Dependent, Inherited Real Risk, i.e., local microcirculatory remodelling,  localized in well-defined breast quadrant(s), and characterized by newborn-pathological, type I, subtype a) oncological, Endoarteriolar Blocking Devices (8, 9).

In addition, testing for mutations of breast cancer susceptibility genes or for their diminished expression adds to our ability to assess breast cancer risk at an individual level. Really, we cannot localise in one, or more, mamma quadrant the possible breast cancer risk in BRCA 1 and BRCA 2, as well as a lot of other gene mutations-positive women (and men!).

Quantum Biophysical Semeiotics (http://www.semeioticabiofisica.it, Breast Cancer in Practical Application; Oncological Terrain, and www.sisbq.org) allows doctor to recognize firstly oncological terrain  in a quantitative way, and then, but “not” in all cases, of course, breast cancer inherited real risk. As a matter of fact, individuals with oncological terrain do not show generally real risk in all biological systems (3). Interestingly, the absence of both Oncological Terrain and breast oncological “Inherited Real Risk”, the later in a subject with Oncological Terrain, excludes beyond every doubt the possibility of occurrence of breast cancer (2, 3-8). As a consequence, we can perform nowadays an efficacious clinical, primary prevention of breast cancer (4), on very large scale, based on the Single Patient Based Medicine (5, 10).

Finally, “real” sentinel lymphonodes are trigger-points for autoimmune syndrome, bedside diagnosed in a few seconds (3, 4)

Regarding the healing of  Oncological Terrain-Dependent Inherited Real Risk, I invite the readers to visit above-mentioned websites.

In a few words, under Mediterranean modified Diet (a paper in press by Bentham Current Nutrition & Food Science) , etymologically speaking, Melatonin-Coniugated, according to Di Bella – Ferrari (or other efficient Melatonin), Thermal Sulfidrilic Water (I have studied the water of “La Puzzola, Porretta Terme, Bologna); a unique application of Cem Tech a russish quantum-devices, Oncological Terrain and Oncological Inherited Real Risk disappear, allowing me to state that Breast Cancer is defeated by Quantum Biophysical Semeiotics, the “Professors” not yet!

References
1) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno oncologico. Travel Factory SRL., Roma, 2004.

http://www.travelfactory.it/semeiotica_biofisica.htm

2) Stagnaro Sergio.   Overloking Oncological Terrain and oncological Real Risk, no paper is up-dated!  18 January 2008, Annals of Internal Medicine  http://www.annals.org/cgi/eletters/147/11/775

3)  Stagnaro Sergio.  There is another clinical, and overlooked tool, reliable in breast cancer prognosis evaluation, BioMed Central, 2005.  http://www.biomedcentral.com/1471-2407/5/70/comments#204473

4) Stagnaro-Neri M., Stagnaro S. Cancro della mammella: : prevenzione primaria e diagnosi precoce con la percussione ascoltata. Gazz. Med. It.; Arch.  Sc.  Med. 152, 447, 1993.
5)  Stagnaro Sergio. A new way in the war against breast cancer, fortunately.

 Breast Cancer Res 2005,. http://breast-cancer research.com/content/7/2/R210/comments
4)  Stagnaro Sergio.    Rinaldi’s Sign in bedside Diagnosing   Di Bella’s Oncological Terrain, and overt Cancer, solid and liquid. Lectio Magistralis, II Convegno Nazionale della SISBQ, Chiusi (Siena), 28-29 maggio 2011. http://www.sisbq.org/acts-of-the-second-conference.html

http://www.sisbq.org/uploads/5/6/8/7/5687930/rinaldisign_eng.pdf

5) Stagnaro S., Stagnaro-Neri M. Single Patient Based Medicine. La Medicina Basata sul Singolo Paziente: Nuove Indicazioni della Melatonina. Travel Factory SRL., Roma, 2005. http://www.travelfactory.it/semeiotica_biofisica.htm

6) Stagnaro Sergio.  “Genes, Oncological Terrain, and Breast Cancer”.  World Journal of  Surgical Oncology., 2005, http://www.wjso.com/content/3/1/45/comments#205475

7) Stagnaro  Sergio Mitochondrial Bed-Side Evaluation: a new Way in the War against Cancer (21 December 2005). Cancer Cell International  http://www.cancerci.com/content/5/1/34/comments#218502

8) Stagnaro Sergio. Reale Rischio Semeiotico Biofisico. I Dispositivi Endoarteriolari di Blocco neoformati, patologici, tipo I, sottotipo a) oncologico, e b) aspecifico. Ediz. Travel Factory, www.travelfactory.it, Roma, 2009.

9) Caramel S., Stagnaro S. The role of mitochondria and mit-DNA in Oncogenesis. http://ilfattorec.altervista.org/mitDNA&oncogenesis_english.pdf;  Quantum Biosystems 2010, 2, 221-248

 

10) Stagnaro Sergio. Quantum biophysical semeiotics. NeuroQuantology | September 2011 | Vol 9 | Issue 3 | Page 459‐467. http://www.neuroquantology.com/index.php/journal/issue/current/showToc

 

11) Sergio Stagnaro and Simone Caramel (2011). The genetic Reversibility in Oncology, Journal of Quantum Biophysical Semeiotics, http://www.sisbq.org/uploads/5/6/8/7/5687930/reverse_oncology.pdf

12) Sergio Stagnaro.  Oncological Terrian’s Paramount Role in Fighting Cancer . 2012 MENA Health World, January 2012, Vol. 1, Pg 16. http://www.mhwmag.net/levelthree.aspx?magazine_subsection_id=3047&all_lk_id=252&magazine_section_id=1&magazine_id=4