“Tutti sanno che una cosa è impossibile da realizzare,
finché arriva uno sprovveduto che non lo sa e la inventa”. (Einstein)
JAMA al LINK https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2755671?guestAccessKey=6a1d3d08-213e-4f31-a674-e6311308cf79&utm_source=silverchair&utm_campaign=jama_network&utm_content=onc_weekly_highlights&cmp=1&utm_medium=email riferisce il procedimento delirante per riconoscere il cancro polmonare precocemente.
Nel mio commento, che mai sarà pubblicato nel sito di JAMA, ho illustrato la diagnosi clinica del cancro polmonare, secondo la Semeiotica Biofisica Quantistica, affidabile nel riconoscere il Reale Rischio Congenti di Cancro ed eliminarlo con TQMR.
Ascertaining 26 gene mutation to recognize individuals at possible risk of lung cancer is expensive and impossible on vast scale, particularly in under-developed and developing countries. On the other hand, it is an impossible and useless enterprise, fighting lung cancer with the aid of a secondary, expensive, realizable in well-developed countries, as USA, by means of positron emission tomography computerized tomography (PET-CT).
Fortunately, classical Baserga’sign, I described in earlier article (1), proved to be useful in bed-side recognizing iron-deficiency syndrome. In fact, due to iron deficiency, erythropoietin cannot stimulate physiologically bone-marrow, as it happens in healthy subject, provoking Baserga’s sign.
In a few words, in healthy, lying down in supine position, psycho-physically relaxed with open eyes to prevent melatonin secretion, mean-intense digital pressure applied upon middle line of sternal body, brings about gastric aspecific reflex after a latency time of exact 10 sec., indicating that bone-marrow activity is normal, according to Angiopathy Theory (1-4).
On the contrary, after stimulation of renal erythropoietin secretion by pinching lateral abdominal skin for about 15sec., the second evaluation shows a statistically lowered latency time: e.g., 6 sec., due to bone-marrow increased microcirculatory activity, facilitating local histangic acidosis under experimental condition.
Notoriously, exclusively in presence of normal iron tissue level, endogenous erythropoietin can act on bone marrow. In fact, in iron deficiency syndrome, the lowering of sternum-gastric aspecific reflex, i.e., Retyculo-Endothelial System Hyperfunction Syndrome (RESH) (2), is clearly compromised, in inverse relation to the seriousness of underlying iron deficiency
Interestingly, in lung cancer (e.g. adenocarcinoma), I observed a “variant” form of the Baserga’sign. Really, I suspected that stimulating cutaneous trigger-points, related to lung cancer even in the initial stage of Cancer, i.e., Inherited Real Risk of lung cancer(1-6) by digital pressure, would provoke the output of tumour cell products, which in turn stimulate bone-marrow, at the moment partially suppressed in its function.
According to Max Born, a new theory must be “mad” enough to be true.
In healthy, mean-intense digital pressure (500 dyne/cm.2), applied on skin projection area of diverse lung lobes (= stimulation of pulmonary trigger-points), brings about gastric aspecific reflex after exactly 8 sec. latency time, and the basal latency time of Rethiculo-Endothelial System Hyperfunction Syndrome (2-6) persists identical, under the same condition, when the stimulation of lung trigger-points lasts about 15-20 sec.
In fact, the latency time of sternum-aspecific gastric reflex, i.e., RESH (= mean-intense digital pressure applied upon the middle line of sternal body, and/or iliac crests) persists identical to the basal one: lt 10 sec., also after stimulating the trigger-points of healthy lung for about 15-20 sec., indicating absence of erytropoietin-like substance secretion from lung (or every biological system, of course).
On the contrary, in case of lung cancer Inherited Real Risk and overt lung cancer, under the same condition (= mean-intense digital pressure, applied precisely on disorder cutaneous projection area, lasting 15-20 sec.), one observes a significant reduction of RESH latency time, lowering from 10 sec. to 6 sec., in relation to the seriousness of underlying disorder.
In addition, in presence of lung cancer Inherited Real Risk, characterized by the presence of newborn-pathological, type I, subtype a), oncological, Endoarteriolar Blocking Devices (6), interestingly, basal lt. of lung-aspecific gastric aspecific reflex may result normal (i.e., 8 sec.), but reflex duration is pathologically 4 sec. or more (NN: lower than 4 sec.: parameter value of paramount diagnostic importance, correlated with local Microcirculatory Functional Reserve, MFR), and finally follows the pathological tonic Gastric Contraction, absent under physiological conditions, and typical of oncological disease.
In presence of overt lung cancer, even in its initial stage, latency time of lung-gastric aspecific reflex lowers significantly (NN = 8 sec.), reflex duration is increased (more than 4 sec.), followed, without delay, by “pathological” tonic Gastric Contraction (tGC).
Interestingly, I emphasise the central role played by Musella’s Sign in bedside detecting Lung Cancer, starting from its Inherited Real Risk, based on no-local Realm in biological systems (www.sisbq.org and www.semeioticabiofisica.i).
In healthy, intense digital pressure (1,000 dyne/cm.2), applied upon every thoracic area (= no-local reality in biological systems), does not bring about gastric aspecific Reflex.
On the contrary, in patient involved by lung cancer, starting from its Inherited Real Risk, simultaneously appears a gastric aspecific Reflex, followed by tonic Gastric Contraction, typical of malignancy. The intensity of parameter values parallel the seriousness of underlying disorder.
I suggest the above described quantum-biophysical-semeiotic signs as worthy of attention in daily practice, although further investigations are necessary. In fact, in a long experience, those signs proved to be a paramount clinical tool in lung cancer primary prevention as well as in the war against pulmonary malignancy.
Finally, after bed-side diagnosing Lung Inherited Real Risk, physician can removed it under Reconstructin Mitochondrial Quantum Therapy.
1) Stagnaro S. Segno di Baserga: diagnosi clinica semeiotico-biofisica della carenza di ferro mediante valutazione dell’attività midollare dell’eritropoietina endogena. www.semeioticabiofisica.it, URL: http://www.semeioticabiofisica.it/semeioticabiofisica/Documenti/Eng/Segno%20Baserga%20variant%20engl.doc
2) Stagnaro S., Sindrome percusso-ascoltatoria di Iperfunzione del Sistema Reticolo-Istiocitario. Min. Med. 74, 479, 1983 (Medline)
3) Stagnaro-Neri M., Stagnaro S., Semeiotica Biofisica del torace, della circolazione ematica e dell’anticorpopoiesi acuta e cronica. Acta Med. Medit. 13, 25, 1997.
5) Stagnaro-Neri M., Stagnaro S. Introduzione alla Semeiotica Biofisica. Il Terreno Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it/semeiotica_biofisica.htm.
6) Stagnaro S. Reale Rischio Semeiotico-Biofisico. Ruolo diagnostico e patogenetico dei Dispositivi Endoarteriolari di Blocco neoformati-patologici tipo I, a) e b). Ed. Travel Factory, Rome, www.travelfactory.it, Luglio 2009.
7) Caramel S., Stagnaro S. The role of mitochondria and mit-DNA in Oncogenesis. Quantum Biosystems 2010, 2, 221-248, http://www.quantumbiosystems.org/admin/files/QBS%202(1)%20250-281.pdf