“Tutti sanno che una cosa è impossibile da realizzare, finché arriva uno sprovveduto che non lo sa e la inventa” Albert Einstein
L’Infarto Miocardico Acuto (IMA), prima della consegna alla Letteratura dei dati delle mie ricerche cliniche iniziate nell’autunno del 2001, era erroneamnte definito “improvviso e imprevisto”.
Potremmo prevenire l’IMA su vasta scala se ai Medici venisse insegnato come diagnosticare ed eliminare il Reale Rischio Congenito di IMA, dipendente dalla Costituzione Aterosclerotica, trasmesso dalla madre, diagnosticato con un fonendoscopio dalla nascita e definitivamente guarito con Terapia Quantistica Mitocondriale Ristrutturante, TQMR (1-26).
Purtroppo, questi datati progressi della Cardiologia Semeiotico-Biofisico-Quantistica in Italia non sono ancora conosciuti, anche se milioni di italiani traggono beneficio dalla TQMR, grazie ai miei suggerimenti sia consegnati ad Internet sia inviati confidenzialmente via mail.
E’ triste e desolante assistere impotente alla Strage di Innocenti compiuta ogni giorno nella assoluta indifferenza di tanti probiviri. In realtà, per ammissone generale, è giustificato definire l’IMA una delle epidemie in aumento, accanto a quella ben nota di morbillo.
https://www.cardiologicomonzino.it/doc/1150/71f997ac99cc4d319a3ad6a5e2e18bac/
“INFARTO
Ogni anno in Italia circa 120 mila persone sono colpite da infarto. Di queste, circa 25 mila muoiono prima di arrivare in ospedale. Ma fra i 95 mila che arrivano in un centro di cura la mortalità è solo del 10,95%. Potrebbe essere ancora dimezzata”.
La mortalità per IMA in Italia potrebbe essere quasi del tutto eliminata se i Destinatari di questa Lettera leggessero con la dovuta attenzione il recente commento che l’autorevole rivista del Regno Unito ha pubblicato nel suo sito il 4 luglio del 2018:
https://bmjopen.bmj.com/content/8/6/e020692.responses
Article.
Dorsey-Treviño, Edgar Gerardo et al “Systematic review and meta-analysis of the effect of SGLT-2 inhibitors on microvascular outcomes in patients with type 2 diabetes: a review protocol.” BMJ Open 8.6 (2018): e020692. Web. 04 July. 2018.
There is a fundamental but overlooked limitation of this study
Sergio Stagnaro, Simone Caramel and Marco Marchionni
Published on: 4 July 2018
There is a fundamental but overlooked limitation of this study
o Sergio Stagnaro, Director Quantum Biophysical Semeiotic Research Laboratory
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- Other Contributors: SimoneCaramel, Presidente, MarcoMarchionni, Vice-Presidente
The data of such a study are fundamentally biased. As a matter of facts, the Authors do not refer to an essential data: the presence of the CVD Inherited Real Risk of enlisted subjects. To declare the real microvascular outomes in patients with Type 2 Diabetes Mellitus under treatment with SGLT-2, only individuals are to be enrolled, involved by ATS Constitution-Dependent, Inherited Real Risk f CVD. (1-5)
References.
1) Stagnaro-Neri M., Stagnaro S., Deterministic Chaos, Preconditioning and Myocardial Oxygenation evaluated clinically with the aid of Biophysical Semeiotics in the Diagnosis of ischaemic Heart Disease even silent. Acta Med. Medit. 13, 109, 1997
2) Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial Oxygenation and Biophysical-Semeiotic Preconditioning. International Atherosclerosis Society. www.athero.org, 29 April, 2009 http://www.athero.org/commentaries/comm907.asp
3) Stagnaro Sergio. Role of Coronary Endoarterial Blocking Devices in Myocardial Preconditioning – c007i. Lecture, V Virtual International Congress of Argentine Cardiology. http://www.fac.org.ar/qcvc/llave/c007i/stagnaros.php
4) Sergio Stagnaro and Simone Caramel (2013). The Inherited Real Risk of Coronary Artery Disease, Nature PG., EJCN, European Journal Clinical Nutrition, Nature PG., 67, 683 (June 2013) | doi:10.1038/ejcn.2013.37, http://www.nature.com/ejcn/journal/v67/n6/full/ejcn201337a.html. [MEDLINE].
Possediamo uno strumento efficace e non costoso per fermare l’epidemia in aumento di IMA. Purtroppo, per realizzare questo traguardo occorre la volontà di tutti, piuttosto che ingenti quantità di danaro.
Bibliografia
1) Sergio Stagnaro and Simone Caramel (2012). Quantum Biophysical Semeiotics Microcirculatory Theory of Arteriosclerosis – www.sisbq.org, Journal of Quantum Biophysical Semeiotics, http://www.sisbq.org/uploads/5/6/8/7/5687930/ats_qbs__mctheory.pdf
2) Stagnaro Sergio. Quantum-Biophysical-Semeiotic bedside Detecting Atherosclerosis from initial, asymptomatic Stage. Inherited real Risk. 23 May 2009 http://sciphu.com, http://wwwshiphusemeioticscom-stagnaro.blogspot.com/2009/05/quantum-biophysical-semeiotic-bedside.html
3) Sergio Stagnaro, Use of multiple markers and improvement of the prediction model for cardiovascular mortality, www.nature.com, 21 May, 2008 http://network.nature.com/forums/pmgs/1587?page=1
5) Sergio Stagnaro Bed-side biophysical semeiotic recognizing CAD “real risk” and overt CAD, event silent.l: (18 October 2003). www.bmj.com, http://www.bmj.com/cgi/eletters/327/7420/895
6) Sergio Stagnaro Assessing NK cell compartment in individuals with CAD Inherited Real Risk. Immunity & Aging, (14 May 2007), http://www.immunityageing.com/content/4/1/3/comments
7) Sergio Stagnaro. Bedside Biophysical-Semeiotic Recognizing CAD Real Risk and silent CAD. Journal Review, http://journalreview.org/v2/articles/view/16449729.html
8) Sergio Stagnaro. A Clinical Biophysical-Semeiotic Contribution reliable in prompt recognizing CAD, even silent. BMC.Cardiovascular Disorders, 2005, http://www.biomedcentral.com/1471-2261/5/5/comments
9 Stagnaro-Neri M., Stagnaro S., Deterministic Chaos, Preconditioning and Myocardial Oxygenation evaluated clinically with the aid of Biophysical Semeiotics in the Diagnosis of ischaemic Heart Disease even silent. Acta Med. Medit. 13, 109, 1997
10) Sergio Stagnaro. We need clinical tool in bedside evaluating drug efficacy. CMJA, 2006, http://www.cmaj.ca/cgi/eletters/174/12/1715
11) Sergio Stagnaro. A Clinical Method far better than Blood Cell Count in CAD Primary Prevention. www.bmj.com, 2005, http://www.bmj.com/cgi/eletters/330/7493/690
12) Sergio Stagnaro. Biophysical Semeiotics is really useful in order to bed-side recognizing heart ischaemic disease, even before its onset, i.e., real risk of coronary artery disease. BMC. Cardiovascular Diseases, 2004,
http://www.biomedcentral.com/1471-2261/3/12/comments
13) Sergio Stagnaro and Simone Caramel (2012). Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Bedside Diagnosis. Morosini’s Syndrome. www.sisbq.org, Journal of Quantum Biophysical Semeiotics, http://www.sisbq.org/uploads/5/6/8/7/5687930/arvdc_morosinis_syndrome_article.pdf
14) Sergio Stagnaro Biophysical-Semeiotic Diagnosing Cad “real” risk, as well as pre-clinical and clinical CAD. www.bmj.com, (12 September 2003) http://bmj.bmjjournals.com/cgi/eletters/327/7415/591
15) Sergio Stagnaro Bedside Biophysical Semeiotic Evaluation of Acute Phase Proteins. Ann Family Med. 2008, http://www.annfammed.org/cgi/eletters/6/2/100
16) Sergio Stagnaro. EBM “and” Single Patient Based Medicine, Medical News today, 2007, http://www.medicalnewstoday.com/youropinions.php?opinionid=23466
17) Sergio Stagnaro. Inherited Real Risk of CAD and Cancer, www.nature.com, 2008, http://blogs.nature.com/news/thegreatbeyond/2008/01/can_shining_lights_on_your_hea_1.html
19) Sergio Stagnaro. Without CAD Inherited Real Risk, All Environmental Risk Factors of CAD are innocent Bystanders. Canadian Medical Association Journal. CMAJ, 14 Dec 2009, http://www.cmaj.ca/cgi/eletters/181/12/E267#253801
20) Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial Oxygenation and Biophysical-Semeiotic Preconditioning. International Atherosclerosis Society. www.athero.org, 29 April, 2009 http://www.athero.org/commentaries/comm907.asp
21) Stagnaro Sergio. Role of Coronary Endoarterial Blocking Devices in Myocardial Preconditioning – c007i. Lecture, V Virtual International Congress of Argentine Cardiology. http://www.fac.org.ar/qcvc/llave/c007i/stagnaros.php
22) Sergio Stagnaro and Simone Caramel. The Key Role of Vasa Vasorum Inherited Remodeling in QBS Microcirculatory Theory of Atherosclerosis. Frontiers in Epigenomics and Epigenetics. Front Genet. 2013; 4: 55. Published online 2013 April 16. doi: 10.3389/fgene.2013.00055 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627131/ [MEDLINE]
23) Sergio Stagnaro and Simone Caramel. The Inherited Real Risk of Coronary Artery Disease, Nature PG., EJCN, European Journal Clinical Nutrition, Nature PG., http://www.nature.com/ejcn/journal/v67/n6/full/ejcn201337a.html [MEDLINE]
24) Sergio Stagnaro and Simone Caramel (2012). Quantum Biophysical Semeiotics Microcirculatory Theory of Arteriosclerosis, Journal of Quantum Biophysical Semeiotics.
25)Stagnaro Sergio. Bedside Evaluation of CAD biophysical-semeiotic inherited real risk under NIR-LED treatment. EMLA Congress, Laser Helsinki August 23-24, 2008. “Photodiagnosis and photodynamic therapy”, Elsevier, Vol. 5 suppl 1 august 2008 issn 1572-1000.
26) Caramel S., Marchionni M., Stagnaro S. Morinda citrifolia Plays a Central Role in the Primary Prevention of Mitochondrial-dependent Degenerative Disorders. Asian Pac J Cancer Prev. 2015;16(4):1675. http://www.ncbi.nlm.nih.gov/pubmed/25743850[MEDLINE]