Semeiotica Biofisica Quantistica. Il Nuovo Rinascimento della Medicina. www.sisbq.org

Stagnaro’s *Sign in Recognizing  gastrointestinal Disorders, even initial or symptomless, regardless of their Nature.

Introduction.
The definition of Quantum Biophysical Semeiotics – QBS – was coined by my friend Paolo Manzelli (1) (See Bibliography in the site http://www.semeioticabiofisica.it).
The use of quantum mechanics evolution applied to biology, has finally illuminated the nature of complex pathogenic mechanisms underlying several QBS signs, utilizing quantum entanglement, after a long wait for a satisfactory explanation that the reductive deterministic mechanics has not been able to provide because of his limited world view, considered to be formed only by Matter and
Vibratory Energy, ignoring completely the Energy-Information (2-4).
In previous articles I have clinically demonstrated that in biological systems it does exist the non local reality next to the local one, in which different is the nature of the transmission of Energy-Information, this transmission present in truth only in the second case where there is consumption of energy and of time in information processing (1-4).
In contrast, in the non-local reality, characterized by a matrix space / time, but with four dimensional  and 2DS 2DT, based on “Entanglement Theory”, the information is simultaneously transmitted by resonance and is made without any transfer.
“This is for example when two simultaneous actions occurring at the same time, as when firecracker explodes at a distance while others shine resonance firecrackers quite distant, but it has been possible to transfer any of sparks” (Manzelli, personal communication).
The use of these new concepts of Quantum Biophysics in Medicine proved to be of essential importance in-depth understanding of many signs, syndromes and QBS tests, and especially in the
diagnosis, in the therapeutic monitoring, in research, as evidenced now by a considerable literature
(1-50).

Stagnaro’ Sign.
It is generally admitted that gastrointestinal disorders, not dependent of their nature, are recognized
later if symptomless or initial. On the other hand, the best therapeutic results are obtained if diagnosis is done early. In following a paramount sign, easy to apply at the bedside, which proved to be reliable in my long clinical experience, is fully described.
In health, “intense” stimulation (= pinching) of the skin, located immediately above the jugulum, along middle line of the neck, is not accompanied “simultaneously” by the gastric aspecific reflex. (Fig. 1). Physician is allowed to exclude gastrointestinal disorder.
Figure 1

On the contrary, in the presence of whatever disorder of gastroistestinal tract, independent of its nature, inflammation, cystic, oncological, etc.. “simultaneously” to the stimulation physician observes the gastric aspecific reflex, whose intensity correlates with the severity of the underlying disorder: a positive Stagnaro’s Sign.
Interestingly, in the presence of gastro-intestinal cancer, the reflex is immediately followed by the typical tonic Gastric Contraction (5, 47 – 49). We must be cautious because also in presence of Appendicitis such a tonic Gastric Contraction is present (51-53).
At this point, having established the presence of a gastrointestinal disorder, the physician should
proceed with the investigation of its location, diagnosing the exact nature, based on awful number
of signs, part of them specific, provided by the Quantum Biophysical Semiotics (1-38).

Conclusions.
Since 2007, Quantum Biophysical Semeiotics was greatly enhanced and made more effective by the
contribution afforded by quantum physics, both in terms of clinical research, and on that of the daily
practical application, so that the boundaries of his domain had a great expansion .
It is well known, for example, that so far the clinical diagnosis of whatever gastrointestinal disorder
is often difficult at the bedside, especially if in initial or symptomless stages.
In fact, it is very difficult clinical diagnosis, made out on the basis of reports of symptomatology
for imaging, from laboratory and histology test. Notoriously, the traditional physical semeiotics does not allow the medical finding of Inherited Real Risk of common disorders, including tumors, malignant or benign.
However, based on personal experience with the Quantum Biophysical Semiotics, I am authorized
to state that in the future can be detected for much more numerous cases of disorders in initial stage, when doctors around the world will be able to use the original semiotics, which allows faster thegeneric diagnosis of malignant vascular tumor, whose precise diagnosis will be made in a timely manner in subjects rationally selected on the basis of several clinical signs of malignancy. As for the easiest method to use, just remember that “mean to moderate” digital pressure, applied directly over whatever biological system projection, through the numerous signs and QBS maneuvers, as gastric aspecific reflex, followed by tonic Gastric Contraction, complete SIRSI, Domenichini Sign, Daneri’s Sign with duration of 4.5 sec. , an increase of Acute Phase Proteins, Acute antibody
synthesis, local microcirculatory activation type II, and III, dissociated, etc. (20-50)

On the contrary, if the stimulation exerted on any gastrointestinal tract, particularly practical is “intense” pinching of the skin, located immediately above the jugulum, along middle line of the neck, it causes in the related tissue associated microcirculatory activation, type I, Energy Vibratory
(ATP) increases and thus an higher EI, pure and catalytic energy: the reality in the biological system is both local and non-local one.
For the phenomenon of resonance, a possible bone lesion at a distance is “simultaneously” stimulated, producing a number of reflections (gastric aspecific reflex followed by tonic Gastric Contraction just in case there is cancer), depending on the nature of the disease itself.

Stagnaro’s Sign is based on quantum scientific knowledge, characterized by entanglement, which
allows to exclude just in one second the presence of gastrointestinal diseases. In fact, once recognized in just a second the presence of a gastrointestinal lesion, physician has to ascertain its
real nature. Thus, doctor will locate the alteration and accurately diagnose the cause based on the
many signs provided by the Quantum Biophysical Semiotics.

References.

1) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica: Realtà non-locale in Biologia.
Dicembre 2007, http://www.fceonline.it/images/docs/lory.pdf
2) Stagnaro S. e Manzelli P. Semeiotica Biofisica Endocrinologica: Meccanica Quantistica e
Meccanismi d’Azione Ormonali. Dicembre 2007,
http://www.fcenews.it/index.php?option=com_content&task=view&id=816&Itemid=45
3) Sergio Stagnaro. Insulin, Adipogenesis, Cancer: an intriguing relation! PLoS, 13 July 2009,
http://www.plosone.org/annotation/listThread.action;jsessionid=269333E6C38DAE33203F859084
8855C0.ambra01?inReplyTo=info%3Adoi%2F10.1371%2Fannotation%2F1fc8961f-7e84-42d9-
bcea-4443873cbf96&root=info%3Adoi%2F10.1371%2Fannotation%2F1fc8961f-7e84-42d9-bcea-
4443873cbf96
4) Stagnaro S. e Manzelli P. Natura Quantistica di una Originale Manovra Semeiotico-Biofisica di
Epatopatia . Dicembre 2007,
http://www.fcenews.it/index.php?option=com_content&task=view&id=862&Itemid=45
5) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno
oncologico”. Travel Factory SRL., Roma, 2004. http://www.travelfactory.it
6) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale
Rischio” Oncologico. Ediz. Travel Factory, Roma, 2004.
7) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico-Biofisiche.Strumento clinico
fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine.
Ediz. Travel Factory, Roma, 2004. http://www.travelfactory.it
8) Stagnaro Sergio. Single Patient Based Medicine: its paramount role in Future Medicine. Public
Library of Science. http://medicine.plosjournals.org/perlserv/?request=read-response
9) Stagnaro S., Stagnaro-Neri M., Single Patient Based Medicine. La Medicina Basata sul Singolo
Paziente: Nuove Indicazioni della Melatonina. Travel Factory, Roma, 2005.
http://www.travelfactory.it/
10) Stagnaro Sergio Biophysical-Semeiotic Diabetic Constitution. Cyber Lecture,
http://www.indmedica.com, 2006, http://cyberlectures.indmedica.com/show/60/1/Diabetic_Constitution
11) Stagnaro Sergio. Pre-Metabolic Syndrome and Metabolic Syndrome: Biophysical-Semeiotic
Viewpoint. http://www.athero.org, 29 April, 2009. http://www.athero.org/commentaries/comm904.asp
12) Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype
B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial
Oxygenation and Biophysical-Semeiotic Preconditioning. http://www.athero.org, 29 April, 2009
http://www.athero.org/commentaries/comm907.asp
13) Stagnaro Sergio. Il “Reale Rischio” Semeiotico-Biofisico. http://www.piazzettamedici.it/.
URL:http://www.piazzettamedici.it/professione/professione.htm
14) Stagnaro Sergio. Reale Rischio Semeiotico Biofisico. I Dispositivi Endoarteriolari di Blocco
neoformati, patologici, tipo I, sottotipo a) oncologico, e b) aspecifico. Ediz. Travel Factory,
http://www.travelfactory.it, Roma, 2009.
15) Stagnaro Sergio. New bedside way in Reducing mortality in diabetic men and women. Ann. Int.
Med. http://www.annals.org/cgi/eletters/0000605-200708070-00167v1
16) Stagnaro S., West PJ., Hu FB., Manson JE., Willett WC. Diet and Risk of Type 2 Diabetes. N
Engl J Med. 2002 Jan 24;346(4):297-298. [Medline]
17) Stagnaro Sergio. Epidemiological evidence for the non-random clustering of the components of
the metabolic syndrome: multicentre study of the Mediterranean Group for the Study of Diabetes.
Eur J Clin Nutr. 2007 Feb 7; [Medline]
18) Stagnaro Sergio. Lettera di un medico in pensione ad un neolaureato, aggiornata e
commentata.www.mednat.org, 22 marzo 2009. http://www.mednat.org/curriculum_stagnaro.htm
19) Stagnaro S., Stagnaro-Neri M. Valutazione percusso-ascoltatoria del Diabete Mellito. Aspetti
teorici e pratici. Epat. 32, 131, 1986
20) Sergio Stagnaro. Biophysical-Semeiotic Dyslipidaemic Constitution. Cyber Lecture,
http://www.indmedica.com , 2006, http://cyberlectures.indmedica.com/show/50/1/Biophysical-
Semeiotic_Dyslipidaemic_Constitution
21) Stagnaro-Neri M., Stagnaro S., La sindrome percusso-ascoltatoria da carenza di Carnitina. Clin.
Ter. 145, 135, 1994 [Medline]
22) Stagnaro-Neri M., Stagnaro S., Semeiotica Biofisica: valutazione clinica del picco precoce della
secrezione insulinica di base e dopo stimolazione tiroidea, surrenalica, con glucagone endogeno e
dopo attivazione del sistema renina-angiotesina circolante e tessutale – Acta Med. Medit. 13, 99,
1997.
23) Stagnaro Sergio. Middle Ages of today’s Medicine, Overlooking Quantum-Biophysical-
Semeiotic Constitutions and Related Inherited Real Risk. http://sciphu.com November 4, 2008.
http://sciphu.com/2008/11/meadle-ages-of-todays-medicine.html
24) Stagnaro Sergio. Il test Semeiotico-Biofisico della Osteocalcina nella prevenzione primaria del
diabete mellito. http://www.fce.it Febbraio 2008.
http://www.fcenews.it/index.php?option=com_content&task=view&id=909&Itemid=47
25) Sergio Stagnaro. New Renaissance in Medicina. Prevenzione Primaria del Diabete Mellito tipo
2. Sito del Convegno, http://qbsemeiotics.weebly.com/atti-del-convegno.html, 16 novembre 2010;
http://qbsemeiotics.weebly.com/uploads/5/6/8/7/5687930/newrenaissance_prevenzionet2dm.pdf;
english version http://qbsemeiotics.weebly.com/uploads/5/6/8/7/5687930/report_stagnaro.pdf ;
http://www.semeioticabiofisica.it/semeioticabiofisica/Documenti/Ita/Nuovo%20Rinascimento%20
Medicina%20RELAZIONE%20I%20Congr.doc; english version
http://www.semeioticabiofisica.it/semeioticabiofisica/Documenti/Eng/Nuovo%20Rinascimento%20
eng.doc
26) Stagnaro Sergio. Pivotal PPARs Activity Bed-side Evaluation in Pre-Metabolic Syndrome and
Metabolic Syndrome Primary Prevention. Cardiovascular Diabetology. 2005, 4:13
doi:10.1186/1475-2840-4-13
27) Stagnaro Sergio. Bedside biophysical-semeiotic PPARs evaluation in glucose-lipid metabosism
monitoring. Annals of Family Medicine 2007; 5: 14-20.
http://www.annfammed.org/cgi/eletters/5/1/14
28) Stagnaro Sergio. Pivotal Role of Liver PPARs Activity Bed-side Evaluation in Monitoring
glucidic and lipidic Metabolism. Lipids in Healt and Disease. 02 June 2007,
http://www.lipidworld.com/content/6/1/12/comments#284542
29) Stagnaro Sergio e Paolo Manzelli. L’Esperimento di Lory. Scienza e Conoscenza, N° 23, 13
Marzo 2008. http://www.scienzaeconoscenza.it//articolo.php?id=17775
30) Sergio Stagnaro. La Medicina Occidentale: un Gigante dai Piedi d’Argilla. 4 Gennaio. 2010,
http://www.fcenews.it, http://www.fceonline.it/images/docs/gigante.pdf
31) Stagnaro-Neri M., Stagnaro S., Sindrome di Reaven, classica e variante, in evoluzione
diabetica. Il ruolo della Carnitina nella prevenzione del diabete mellito. Il Cuore. 6, 617, 1993
[Medline]
32 ) Sergio Stagnaro. Without CAD Inherited Real Risk, All Environmental Risk Factors of CAD
are innocent Bystanders. Canadian Medical Association Journal. CMAJ, 14 Dec 2009,
http://www.cmaj.ca/cgi/eletters/181/12/E267#253801
33) Sergio Stagnaro. New Renaissance in Medicine. 01 October 2010, http://www.scivox.com.
http://www.sci-vox.com/stories/story/2010-10-01new+renaissance+in+medicine..html
34) Stagnaro Sergio. Valutazione dell’amiloide insulare nel diabete mellito.
http://www.fceonline.it, 2008, http://www.fceonline.it/wikimedicina/semeiotica-biofisica/211/581-
valutazione-dell-amiloide-insulare-nel-diabete.html; e
http://xoomer.virgilio.it/piazzetta/professione/amiloide.htm
35) Caramel Simone. Primary Prevention of T2DM and Inherited Real Risk of Type 2 Diabetes
Mellitus http://ilfattorec.altervista.org/T2DM.pdf
36) Sergio Stagnaro. Primo neonato negativo per il Terreno Oncologico nato da genitori positivi per
la Variante RESIDUA in trattamento con Melatonina-Coniugata, secondo Di Bella-Ferrari.
http://www.fce.it, 13 aprile 2010, http://www.fceonline.it/images/docs/neonato.pdf; nel sito
http://junior.cybermed.it/index.php?option=com_frontpage&Itemid=36, alle URLs
http://junior.cybermed.it/index.php?option=com_content&task=view&id=1073&Itemid=51
http://www.cybermed.it/index.php?option=com_content&task=view&id=24687&Itemid=134;
http://www.piazzettamedici.it/professione/professione.htm
http://www.liquidarea.com/2010/07/manuels-story-la-melatonina-nella-terapia-del-terrenooncologico/
37) Sergio Stagnaro. New Way in the War against Cancer. Oncological Terrain-Dependent,
Inherited Real Risk based Primary Prevention: Manuel’ Story. 2 May, 2010. http://www.mysun.com. ,
http://www.mysun.co.uk/stagnaro/blog/2010/05/02/new_way_in_the_war_against_cancer._oncolog
ical_terrain-dependent,_inherited_real_risk_based_primary_prevention:_manuel_story, and
http://www.sci-vox.com/stories/story/2010-07-
21manuel%27s+story%3A+a+new+way+in+cancer+primary+prevention.html
38) Sergio Stagnaro. Lettera Aperta alle Neo-Spose. La Storia di Manuel, che nessuno racconta.
http://www.masterviaggi.it Giovedì, 15 Luglio 2010.
http://www.masterviaggi.it/news/categoria_news/40260-lettera_aperta_alle_neospose_
la_storia_di_manuel_che_nessuno_racconta.php
39) Stagnaro Sergio. Oncogenesis is possible exclusively in individuals Oncological Terrainpositive.
http://www.thescientist.com 2007. http://www.the-scientist.com/blog/print/53498/
40) Sergio Stagnaro. There are other, clinical ways in preventing disease transmission through
mitochondria intervention. 15 April, 2010. http://www.thescientist.com, http://www.thescientist.
com/blog/display/57287/
41) Sergio Stagnaro. Il Terreno Oncologico di Di Bella. http://www.fce.it, 11 ottobre 2010,
http://www.fceonline.it/images/docs/terreno%20oncologico.pdf;
http://www.luigidibella.it/cms-web/upl/doc/Documenti-inseriti-dal-2-11
2007/Il%20Terreno%20Oncologico%20di%20Di%20Bella.pdf;
http://www.altrogiornale.org/news.php?extend.6420
42) Stagnaro Sergio. La Diagnostica Psicocinetica migliora l’Esame Obiettivo.
http://www.fcenews.it, 15, giugno 2009. http://www.fcenews.it/docs/diagnostica2.pdf ;
http://www.altrogiornale.org, http://www.altrogiornale.org/news.php?extend.4889;
http://www.nonapritequelportale.com/?q=la-psicocinesi-esiste-funziona;
http://unlocketor.altervista.org/forum/viewtopic.php?t=1192&start=0&postdays=0&postorder=asc
&highlight=&sid=af35aa98b69d6f08d116f65d34b55827;
http://www.spaziomente.com/articoli/La_semeiotica_biofisica_quantistica_corrobora_la_psicocines
i.pdf
43) Curri S. B., Le microangiopatie, a cura di Inverni della Beffa, Arte Grafica S.p.A. Verona, 1986
44) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica condizione necessaria non
sufficiente della oncogenesi. XI Congr. Naz. Soc. It. di Microangiologia e Microcircolaz. Abstracts,
pg 38, 28 Settembre-1 Ottobre, Bellagio
45) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica. X Congr. Naz. Soc. It. di
Microangiologia e Microcircolazione. Atti, 61. 6-7 Novembre, Siena
46) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica. Gazz Med. It. – Asch. Sci,
Med. 144, 423
47) Sergio Stagnaro. Semeiotica biofisica quantistica: diagnosi rapida di reale rischio di
neoplasia e metastasi ossee. http://www.fce.it, 18 Dicembre, 2010.
http://www.fceonline.it/images/docs/metastasi.pdf
48) Stagnaro S., Auscultatory Percussion of Rheumatic Diseases. X European Congress of
Rheumatology. Moscow. 26 June-July, Proceedings, pg 175, 1983.
49) Stagnaro S., Polimialgia Reumatica Acuta Benigna Variante. Clin. Ter. 118, 193 [Medline]
50) Stagnaro Sergio. Lettera Aperta al Ministro della Salute, On Prof. Ferruccio Fazio. Terrorismo
Psicologico Jatrogenetico, Epidemia ignorata ma in aumento. http://www.mednat.org, 22 ottobre 2010.
http://www.mednat.org/Lettera_Aperta_%20Ministro_Salute%202010.pdf ;
http://www.fceonline.it/home-mainmenu-1/bacheca/199-bacheca/97835-lettera-aperta-al-ministrodella-
salute-on-prof-ferruccio-fazio.html
51) Stagnaro S. Bed-side diagnosing acute appendicitis and gastrointestinal diseases. Gut.j.on
line, 2003: http://gut.bmjjournals.com/cgi/eletters/52/5/770-a#100.
52) Stagnaro Sergio.Biophysical-Semeiotic Diagnosis of Appendicitis. 14 aprile 2009, at URL
http://sciphu.com, and at URL http://wwwshiphusemeioticscom-stagnaro.blogspot.com/
53) Stagnaro-Neri M., Stagnaro S., Appendicite. Min. Med. 87, 183 [MEDLINE]
* Dedicated to myself, for the 55 year-long effort to develop physical semeiotics in the Ages of
technological Medicine

* By
Sergio Stagnaro MD
Via Erasmo Piaggio 23/8,
16039 Riva Trigoso (Genoa) Italy
Founder of Quantum Biophysical Semeiotics,
Honorary President of International Society of
Quantum Biophysical Semeiotics (SISBQ)
Stagnaro’s *Sign in Recognizing  gastrointestinal Disorders, even initial or symptomless, regardless of their Nature.

Introduction.
The definition of Quantum Biophysical Semeiotics – QBS – was coined by my friend Paolo Manzelli (1) (See Bibliography in the site http://www.semeioticabiofisica.it).
The use of quantum mechanics evolution applied to biology, has finally illuminated the nature of complex pathogenic mechanisms underlying several QBS signs, utilizing quantum entanglement, after a long wait for a satisfactory explanation that the reductive deterministic mechanics has not been able to provide because of his limited world view, considered to be formed only by Matter and
Vibratory Energy, ignoring completely the Energy-Information (2-4).
In previous articles I have clinically demonstrated that in biological systems it does exist the non local reality next to the local one, in which different is the nature of the transmission of Energy-Information, this transmission present in truth only in the second case where there is consumption of energy and of time in information processing (1-4).
In contrast, in the non-local reality, characterized by a matrix space / time, but with four dimensional  and 2DS 2DT, based on “Entanglement Theory”, the information is simultaneously transmitted by resonance and is made without any transfer.
“This is for example when two simultaneous actions occurring at the same time, as when firecracker explodes at a distance while others shine resonance firecrackers quite distant, but it has been possible to transfer any of sparks” (Manzelli, personal communication).
The use of these new concepts of Quantum Biophysics in Medicine proved to be of essential importance in-depth understanding of many signs, syndromes and QBS tests, and especially in the
diagnosis, in the therapeutic monitoring, in research, as evidenced now by a considerable literature
(1-50).

Stagnaro’ Sign.
It is generally admitted that gastrointestinal disorders, not dependent of their nature, are recognized
later if symptomless or initial. On the other hand, the best therapeutic results are obtained if diagnosis is done early. In following a paramount sign, easy to apply at the bedside, which proved to be reliable in my long clinical experience, is fully described.
In health, “intense” stimulation (= pinching) of the skin, located immediately above the jugulum, along middle line of the neck, is not accompanied “simultaneously” by the gastric aspecific reflex. (Fig. 1). Physician is allowed to exclude gastrointestinal disorder.
Figure 1

On the contrary, in the presence of whatever disorder of gastroistestinal tract, independent of its nature, inflammation, cystic, oncological, etc.. “simultaneously” to the stimulation physician observes the gastric aspecific reflex, whose intensity correlates with the severity of the underlying disorder: a positive Stagnaro’s Sign.
Interestingly, in the presence of gastro-intestinal cancer, the reflex is immediately followed by the typical tonic Gastric Contraction (5, 47 – 49). We must be cautious because also in presence of Appendicitis such a tonic Gastric Contraction is present (51-53).
At this point, having established the presence of a gastrointestinal disorder, the physician should
proceed with the investigation of its location, diagnosing the exact nature, based on awful number
of signs, part of them specific, provided by the Quantum Biophysical Semiotics (1-38).

Conclusions.
Since 2007, Quantum Biophysical Semeiotics was greatly enhanced and made more effective by the
contribution afforded by quantum physics, both in terms of clinical research, and on that of the daily
practical application, so that the boundaries of his domain had a great expansion .
It is well known, for example, that so far the clinical diagnosis of whatever gastrointestinal disorder
is often difficult at the bedside, especially if in initial or symptomless stages.
In fact, it is very difficult clinical diagnosis, made out on the basis of reports of symptomatology
for imaging, from laboratory and histology test. Notoriously, the traditional physical semeiotics does not allow the medical finding of Inherited Real Risk of common disorders, including tumors, malignant or benign.
However, based on personal experience with the Quantum Biophysical Semiotics, I am authorized
to state that in the future can be detected for much more numerous cases of disorders in initial stage, when doctors around the world will be able to use the original semiotics, which allows faster thegeneric diagnosis of malignant vascular tumor, whose precise diagnosis will be made in a timely manner in subjects rationally selected on the basis of several clinical signs of malignancy. As for the easiest method to use, just remember that “mean to moderate” digital pressure, applied directly over whatever biological system projection, through the numerous signs and QBS maneuvers, as gastric aspecific reflex, followed by tonic Gastric Contraction, complete SIRSI, Domenichini Sign, Daneri’s Sign with duration of 4.5 sec. , an increase of Acute Phase Proteins, Acute antibody
synthesis, local microcirculatory activation type II, and III, dissociated, etc. (20-50)

On the contrary, if the stimulation exerted on any gastrointestinal tract, particularly practical is “intense” pinching of the skin, located immediately above the jugulum, along middle line of the neck, it causes in the related tissue associated microcirculatory activation, type I, Energy Vibratory
(ATP) increases and thus an higher EI, pure and catalytic energy: the reality in the biological system is both local and non-local one.
For the phenomenon of resonance, a possible bone lesion at a distance is “simultaneously” stimulated, producing a number of reflections (gastric aspecific reflex followed by tonic Gastric Contraction just in case there is cancer), depending on the nature of the disease itself.

Stagnaro’s Sign is based on quantum scientific knowledge, characterized by entanglement, which
allows to exclude just in one second the presence of gastrointestinal diseases. In fact, once recognized in just a second the presence of a gastrointestinal lesion, physician has to ascertain its
real nature. Thus, doctor will locate the alteration and accurately diagnose the cause based on the
many signs provided by the Quantum Biophysical Semiotics.

References.

1) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica: Realtà non-locale in Biologia.
Dicembre 2007, http://www.fceonline.it/images/docs/lory.pdf
2) Stagnaro S. e Manzelli P. Semeiotica Biofisica Endocrinologica: Meccanica Quantistica e
Meccanismi d’Azione Ormonali. Dicembre 2007,
http://www.fcenews.it/index.php?option=com_content&task=view&id=816&Itemid=45
3) Sergio Stagnaro. Insulin, Adipogenesis, Cancer: an intriguing relation! PLoS, 13 July 2009,
http://www.plosone.org/annotation/listThread.action;jsessionid=269333E6C38DAE33203F859084
8855C0.ambra01?inReplyTo=info%3Adoi%2F10.1371%2Fannotation%2F1fc8961f-7e84-42d9-
bcea-4443873cbf96&root=info%3Adoi%2F10.1371%2Fannotation%2F1fc8961f-7e84-42d9-bcea-
4443873cbf96
4) Stagnaro S. e Manzelli P. Natura Quantistica di una Originale Manovra Semeiotico-Biofisica di
Epatopatia . Dicembre 2007,
http://www.fcenews.it/index.php?option=com_content&task=view&id=862&Itemid=45
5) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno
oncologico”. Travel Factory SRL., Roma, 2004. http://www.travelfactory.it
6) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale
Rischio” Oncologico. Ediz. Travel Factory, Roma, 2004.
7) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico-Biofisiche.Strumento clinico
fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine.
Ediz. Travel Factory, Roma, 2004. http://www.travelfactory.it
8) Stagnaro Sergio. Single Patient Based Medicine: its paramount role in Future Medicine. Public
Library of Science. http://medicine.plosjournals.org/perlserv/?request=read-response
9) Stagnaro S., Stagnaro-Neri M., Single Patient Based Medicine. La Medicina Basata sul Singolo
Paziente: Nuove Indicazioni della Melatonina. Travel Factory, Roma, 2005.
http://www.travelfactory.it/
10) Stagnaro Sergio Biophysical-Semeiotic Diabetic Constitution. Cyber Lecture,
http://www.indmedica.com, 2006, http://cyberlectures.indmedica.com/show/60/1/Diabetic_Constitution
11) Stagnaro Sergio. Pre-Metabolic Syndrome and Metabolic Syndrome: Biophysical-Semeiotic
Viewpoint. http://www.athero.org, 29 April, 2009. http://www.athero.org/commentaries/comm904.asp
12) Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype
B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial
Oxygenation and Biophysical-Semeiotic Preconditioning. http://www.athero.org, 29 April, 2009
http://www.athero.org/commentaries/comm907.asp
13) Stagnaro Sergio. Il “Reale Rischio” Semeiotico-Biofisico. http://www.piazzettamedici.it/.
URL:http://www.piazzettamedici.it/professione/professione.htm
14) Stagnaro Sergio. Reale Rischio Semeiotico Biofisico. I Dispositivi Endoarteriolari di Blocco
neoformati, patologici, tipo I, sottotipo a) oncologico, e b) aspecifico. Ediz. Travel Factory,
http://www.travelfactory.it, Roma, 2009.
15) Stagnaro Sergio. New bedside way in Reducing mortality in diabetic men and women. Ann. Int.
Med. http://www.annals.org/cgi/eletters/0000605-200708070-00167v1
16) Stagnaro S., West PJ., Hu FB., Manson JE., Willett WC. Diet and Risk of Type 2 Diabetes. N
Engl J Med. 2002 Jan 24;346(4):297-298. [Medline]
17) Stagnaro Sergio. Epidemiological evidence for the non-random clustering of the components of
the metabolic syndrome: multicentre study of the Mediterranean Group for the Study of Diabetes.
Eur J Clin Nutr. 2007 Feb 7; [Medline]
18) Stagnaro Sergio. Lettera di un medico in pensione ad un neolaureato, aggiornata e
commentata.www.mednat.org, 22 marzo 2009. http://www.mednat.org/curriculum_stagnaro.htm
19) Stagnaro S., Stagnaro-Neri M. Valutazione percusso-ascoltatoria del Diabete Mellito. Aspetti
teorici e pratici. Epat. 32, 131, 1986
20) Sergio Stagnaro. Biophysical-Semeiotic Dyslipidaemic Constitution. Cyber Lecture,
http://www.indmedica.com , 2006, http://cyberlectures.indmedica.com/show/50/1/Biophysical-
Semeiotic_Dyslipidaemic_Constitution
21) Stagnaro-Neri M., Stagnaro S., La sindrome percusso-ascoltatoria da carenza di Carnitina. Clin.
Ter. 145, 135, 1994 [Medline]
22) Stagnaro-Neri M., Stagnaro S., Semeiotica Biofisica: valutazione clinica del picco precoce della
secrezione insulinica di base e dopo stimolazione tiroidea, surrenalica, con glucagone endogeno e
dopo attivazione del sistema renina-angiotesina circolante e tessutale – Acta Med. Medit. 13, 99,
1997.
23) Stagnaro Sergio. Middle Ages of today’s Medicine, Overlooking Quantum-Biophysical-
Semeiotic Constitutions and Related Inherited Real Risk. http://sciphu.com November 4, 2008.
http://sciphu.com/2008/11/meadle-ages-of-todays-medicine.html
24) Stagnaro Sergio. Il test Semeiotico-Biofisico della Osteocalcina nella prevenzione primaria del
diabete mellito. http://www.fce.it Febbraio 2008.
http://www.fcenews.it/index.php?option=com_content&task=view&id=909&Itemid=47
25) Sergio Stagnaro. New Renaissance in Medicina. Prevenzione Primaria del Diabete Mellito tipo
2. Sito del Convegno, http://qbsemeiotics.weebly.com/atti-del-convegno.html, 16 novembre 2010;
http://qbsemeiotics.weebly.com/uploads/5/6/8/7/5687930/newrenaissance_prevenzionet2dm.pdf;
english version http://qbsemeiotics.weebly.com/uploads/5/6/8/7/5687930/report_stagnaro.pdf ;
http://www.semeioticabiofisica.it/semeioticabiofisica/Documenti/Ita/Nuovo%20Rinascimento%20
Medicina%20RELAZIONE%20I%20Congr.doc; english version
http://www.semeioticabiofisica.it/semeioticabiofisica/Documenti/Eng/Nuovo%20Rinascimento%20
eng.doc
26) Stagnaro Sergio. Pivotal PPARs Activity Bed-side Evaluation in Pre-Metabolic Syndrome and
Metabolic Syndrome Primary Prevention. Cardiovascular Diabetology. 2005, 4:13
doi:10.1186/1475-2840-4-13
27) Stagnaro Sergio. Bedside biophysical-semeiotic PPARs evaluation in glucose-lipid metabosism
monitoring. Annals of Family Medicine 2007; 5: 14-20.
http://www.annfammed.org/cgi/eletters/5/1/14
28) Stagnaro Sergio. Pivotal Role of Liver PPARs Activity Bed-side Evaluation in Monitoring
glucidic and lipidic Metabolism. Lipids in Healt and Disease. 02 June 2007,
http://www.lipidworld.com/content/6/1/12/comments#284542
29) Stagnaro Sergio e Paolo Manzelli. L’Esperimento di Lory. Scienza e Conoscenza, N° 23, 13
Marzo 2008. http://www.scienzaeconoscenza.it//articolo.php?id=17775
30) Sergio Stagnaro. La Medicina Occidentale: un Gigante dai Piedi d’Argilla. 4 Gennaio. 2010,
http://www.fcenews.it, http://www.fceonline.it/images/docs/gigante.pdf
31) Stagnaro-Neri M., Stagnaro S., Sindrome di Reaven, classica e variante, in evoluzione
diabetica. Il ruolo della Carnitina nella prevenzione del diabete mellito. Il Cuore. 6, 617, 1993
[Medline]
32 ) Sergio Stagnaro. Without CAD Inherited Real Risk, All Environmental Risk Factors of CAD
are innocent Bystanders. Canadian Medical Association Journal. CMAJ, 14 Dec 2009,
http://www.cmaj.ca/cgi/eletters/181/12/E267#253801
33) Sergio Stagnaro. New Renaissance in Medicine. 01 October 2010, http://www.scivox.com.
http://www.sci-vox.com/stories/story/2010-10-01new+renaissance+in+medicine..html
34) Stagnaro Sergio. Valutazione dell’amiloide insulare nel diabete mellito.
http://www.fceonline.it, 2008, http://www.fceonline.it/wikimedicina/semeiotica-biofisica/211/581-
valutazione-dell-amiloide-insulare-nel-diabete.html; e
http://xoomer.virgilio.it/piazzetta/professione/amiloide.htm
35) Caramel Simone. Primary Prevention of T2DM and Inherited Real Risk of Type 2 Diabetes
Mellitus http://ilfattorec.altervista.org/T2DM.pdf
36) Sergio Stagnaro. Primo neonato negativo per il Terreno Oncologico nato da genitori positivi per
la Variante RESIDUA in trattamento con Melatonina-Coniugata, secondo Di Bella-Ferrari.
http://www.fce.it, 13 aprile 2010, http://www.fceonline.it/images/docs/neonato.pdf; nel sito
http://junior.cybermed.it/index.php?option=com_frontpage&Itemid=36, alle URLs
http://junior.cybermed.it/index.php?option=com_content&task=view&id=1073&Itemid=51
http://www.cybermed.it/index.php?option=com_content&task=view&id=24687&Itemid=134;
http://www.piazzettamedici.it/professione/professione.htm
http://www.liquidarea.com/2010/07/manuels-story-la-melatonina-nella-terapia-del-terrenooncologico/
37) Sergio Stagnaro. New Way in the War against Cancer. Oncological Terrain-Dependent,
Inherited Real Risk based Primary Prevention: Manuel’ Story. 2 May, 2010. http://www.mysun.com. ,
http://www.mysun.co.uk/stagnaro/blog/2010/05/02/new_way_in_the_war_against_cancer._oncolog
ical_terrain-dependent,_inherited_real_risk_based_primary_prevention:_manuel_story, and
http://www.sci-vox.com/stories/story/2010-07-
21manuel%27s+story%3A+a+new+way+in+cancer+primary+prevention.html
38) Sergio Stagnaro. Lettera Aperta alle Neo-Spose. La Storia di Manuel, che nessuno racconta.
http://www.masterviaggi.it Giovedì, 15 Luglio 2010.
http://www.masterviaggi.it/news/categoria_news/40260-lettera_aperta_alle_neospose_
la_storia_di_manuel_che_nessuno_racconta.php
39) Stagnaro Sergio. Oncogenesis is possible exclusively in individuals Oncological Terrainpositive.
http://www.thescientist.com 2007. http://www.the-scientist.com/blog/print/53498/
40) Sergio Stagnaro. There are other, clinical ways in preventing disease transmission through
mitochondria intervention. 15 April, 2010. http://www.thescientist.com, http://www.thescientist.
com/blog/display/57287/
41) Sergio Stagnaro. Il Terreno Oncologico di Di Bella. http://www.fce.it, 11 ottobre 2010,
http://www.fceonline.it/images/docs/terreno%20oncologico.pdf;
http://www.luigidibella.it/cms-web/upl/doc/Documenti-inseriti-dal-2-11
2007/Il%20Terreno%20Oncologico%20di%20Di%20Bella.pdf;
http://www.altrogiornale.org/news.php?extend.6420
42) Stagnaro Sergio. La Diagnostica Psicocinetica migliora l’Esame Obiettivo.
http://www.fcenews.it, 15, giugno 2009. http://www.fcenews.it/docs/diagnostica2.pdf ;
http://www.altrogiornale.org, http://www.altrogiornale.org/news.php?extend.4889;
http://www.nonapritequelportale.com/?q=la-psicocinesi-esiste-funziona;
http://unlocketor.altervista.org/forum/viewtopic.php?t=1192&start=0&postdays=0&postorder=asc
&highlight=&sid=af35aa98b69d6f08d116f65d34b55827;
http://www.spaziomente.com/articoli/La_semeiotica_biofisica_quantistica_corrobora_la_psicocines
i.pdf
43) Curri S. B., Le microangiopatie, a cura di Inverni della Beffa, Arte Grafica S.p.A. Verona, 1986
44) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica condizione necessaria non
sufficiente della oncogenesi. XI Congr. Naz. Soc. It. di Microangiologia e Microcircolaz. Abstracts,
pg 38, 28 Settembre-1 Ottobre, Bellagio
45) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica. X Congr. Naz. Soc. It. di
Microangiologia e Microcircolazione. Atti, 61. 6-7 Novembre, Siena
46) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica. Gazz Med. It. – Asch. Sci,
Med. 144, 423
47) Sergio Stagnaro. Semeiotica biofisica quantistica: diagnosi rapida di reale rischio di
neoplasia e metastasi ossee. http://www.fce.it, 18 Dicembre, 2010.
http://www.fceonline.it/images/docs/metastasi.pdf
48) Stagnaro S., Auscultatory Percussion of Rheumatic Diseases. X European Congress of
Rheumatology. Moscow. 26 June-July, Proceedings, pg 175, 1983.
49) Stagnaro S., Polimialgia Reumatica Acuta Benigna Variante. Clin. Ter. 118, 193 [Medline]
50) Stagnaro Sergio. Lettera Aperta al Ministro della Salute, On Prof. Ferruccio Fazio. Terrorismo
Psicologico Jatrogenetico, Epidemia ignorata ma in aumento. http://www.mednat.org, 22 ottobre 2010.
http://www.mednat.org/Lettera_Aperta_%20Ministro_Salute%202010.pdf ;
http://www.fceonline.it/home-mainmenu-1/bacheca/199-bacheca/97835-lettera-aperta-al-ministrodella-
salute-on-prof-ferruccio-fazio.html
51) Stagnaro S. Bed-side diagnosing acute appendicitis and gastrointestinal diseases. Gut.j.on
line, 2003: http://gut.bmjjournals.com/cgi/eletters/52/5/770-a#100.
52) Stagnaro Sergio.Biophysical-Semeiotic Diagnosis of Appendicitis. 14 aprile 2009, at URL
http://sciphu.com, and at URL http://wwwshiphusemeioticscom-stagnaro.blogspot.com/
53) Stagnaro-Neri M., Stagnaro S., Appendicite. Min. Med. 87, 183 [MEDLINE]
* Dedicated to myself, for the 55 year-long effort to develop physical semeiotics in the Ages of
technological Medicine

* By
Sergio Stagnaro MD
Via Erasmo Piaggio 23/8,
16039 Riva Trigoso (Genoa) Italy
Founder of Quantum Biophysical Semeiotics,
Honorary President of International Society of
Quantum Biophysical Semeiotics (SISBQ)
Who’s Who in the World (and America)
since 1996
Ph 0039-0185-42315
Cell. 3338631439
http://www.semeioticabiofisica.it
http://www.sisbq.org
dottsergio@semeioticabiofisica.it

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